Grey's Anatomy's very own Camilla Luddington has said fans should brace themselves for season 21, admitting the script left her "shooketh".

The Jo Wilson star will return to ABC's long-running medical drama for a new batch of episodes following a pregnancy twist on season 20.

Speaking with Grey's pal Jessica Capshaw, who plays Arizona Robbins on the show, Luddington explained the new season is almost ready to shoot.

camilla luddington, chris carmack, grey's anatomy season 19
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"I woke up this morning, scrolled through my phone and there it was, sitting in my inbox, the premier episode script of Grey's Anatomy season 21," Luddington said on their Call It What It Is podcast.

"And you know what's so funny and you know this, Jess, we never know what's going to happen. We are not given a heads-up, so I was reading the script in bed this morning and I was shooketh," Luddington continued.

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"I was shooketh, I was amazed and yeah, we're going back next week, I actually have a table read tomorrow."

jessica capshaw, camilla luddington
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Related: Grey's Anatomy star Eric Dane shares reason he was "let go" from show

Set for a September premiere, season 21 of Grey's will reportedly see several cast members appearing in fewer episodes as a cost-cutting measure, whilst protagonist Ellen Pompeo will return to the role of Meredith Grey in at least seven episodes — if not more.

Amongst the actors leaving are Jake Borelli and Midori Francis, who will only star in a few episodes to wrap up their storylines before exiting the show as series regulars.

Grey's Anatomy season 21 will air premiere on Thursday, September 26 at 10pm ET on ABC in the US. Previous seasons are streaming on Disney+ in the UK.

Read more Grey's Anatomy news on our dedicated homepage

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Stefania is a freelance writer specialising in TV and movies. After graduating from City University, London, she covered LGBTQ+ news and pursued a career in entertainment journalism, with her work appearing in outlets including Little White Lies, The Skinny, Radio Times and Digital Spy

Her beats are horror films and period dramas, especially if fronted by queer women. She can argue why Scream is the best slasher in four languages (and a half).